Jo-Ann Passmore

Jo-Ann Passmore is a Senior Lecturer and Medical Scientist at University of Cape Town and National Health Laboratory Service (NHLS).  Prof. Jo-Ann currently heads the Mucosal Immunology laboratory in the Division of Medical Virology at the Institute for Infectious Diseases and Molecular Medicine, University of Cape Town. She obtained her PhD from the University of Cape Town in 1999 in Clinical Immunology and has since been mentored through the MRC (South Africa) Career Development Program (2003-2006), Fogarty AITRP (2004) and the Wellcome Trust with an Intermediate Fellowship in Infectious Diseases (2006-2008). Dr Jo-Ann Passmore's research has focused on studying genital tract adaptive and innate immune responses associated with protection from or susceptibility to sexually transmitted viral diseases including HPV and HIV. She is specifically interested in studying biomarkers for susceptibility and protection to HIV infection, including secreted inflammatory molecules, genital immune activation and HIV-specific immune responses present in the female genital tract. She has published more than 30 papers in international peer reviewed journals on immunity to HIV and HPV and leads a small team of scientists at UCT focusing on immunity at the female genital tract. She has been principal investigator on grants from the South African HIV/AIDS Research Platform (SHARP), the Wellcome Trust, South African AIDS Vaccine Initiative (SAAVI), the HIV Pathogenesis Programme (Doris Duke Charitable Foundation), Medical Research Council (South Africa) and Poliomyelitis Research Foundation and laboratory PI on a grant from the International AIDS Vaccine Initiative (IAVI) to investigate the impact of HIV infection on cervical mucosal responses during chronic and acute HIV infection. She is currently a member of the HIV Vaccine Trials Network (HVTN) Mucosal Working Group which aims at develop methods to investigate HIV-specific immunity in mucosal tissue including the female genital tract.

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